BDBM50517830 CHEMBL4475835

SMILES: Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1F

InChI Key: InChIKey=WHAXCOVHQIMPCN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517830 (CHEMBL4475835) Show SMILES Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1F Show InChI InChI=1S/C19H12F2N4O/c20-13-4-3-6-15(18(13)21)24-19(26)16-11-25-10-12(7-8-17(25)23-16)14-5-1-2-9-22-14/h1-11H,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517830 (CHEMBL4475835) Show SMILES Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1F Show InChI InChI=1S/C19H12F2N4O/c20-13-4-3-6-15(18(13)21)24-19(26)16-11-25-10-12(7-8-17(25)23-16)14-5-1-2-9-22-14/h1-11H,(H,24,26)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024
					More data for this Ligand-Target Pair