BDBM50517840 CHEMBL4545262

SMILES: CCCCCC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1

InChI Key: InChIKey=REWFYBUVJAZDQT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517840 (CHEMBL4545262) Show SMILES CCCCCC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H25ClN2O/c1-2-3-4-8-24(29)20-7-5-6-19(15-20)21-11-14-25-27-23(17-28(25)16-21)18-9-12-22(26)13-10-18/h5-7,9-17,24,29H,2-4,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024
					More data for this Ligand-Target Pair