BDBM50517952 CHEMBL4451554

SMILES: Cc1ccnc(NC(=O)c2ccsc2NC(=O)c2nc3cnccc3s2)n1

InChI Key: InChIKey=ZROVZPJSBYAEMC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Decaprenylphosphoryl-beta-D-ribose oxidase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50517952 (CHEMBL4451554) Show SMILES Cc1ccnc(NC(=O)c2ccsc2NC(=O)c2nc3cnccc3s2)n1 Show InChI InChI=1S/C17H12N6O2S2/c1-9-2-6-19-17(20-9)23-13(24)10-4-7-26-15(10)22-14(25)16-21-11-8-18-5-3-12(11)27-16/h2-8H,1H3,(H,22,25)(H,19,20,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Maharaja Sayajirao University of Baroda Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-thioredoxin tagged Mycobacterium tuberculosis H37Rv DprE1 expressed in Escherichia coli BL21(DE3) using FPR as substrat...				J Med Chem 61: 8563-8593 (2018) Article DOI: 10.1021/acs.jmedchem.8b00281
					More data for this Ligand-Target Pair