null

SMILES: COc1ccc(CCN(C(=O)OC2CCN(C)CC2)c2ccccc2)cc1

InChI Key: InChIKey=IEUILNNAXQDVCX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50518574 (CHEMBL4456775) Show SMILES COc1ccc(CCN(C(=O)OC2CCN(C)CC2)c2ccccc2)cc1 Show InChI InChI=1S/C22H28N2O3/c1-23-15-13-21(14-16-23)27-22(25)24(19-6-4-3-5-7-19)17-12-18-8-10-20(26-2)11-9-18/h3-11,21H,12-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M5 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry method				Bioorg Med Chem Lett 29: 471-476 (2019) Article DOI: 10.1016/j.bmcl.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27SC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50518574 (CHEMBL4456775) Show SMILES COc1ccc(CCN(C(=O)OC2CCN(C)CC2)c2ccccc2)cc1 Show InChI InChI=1S/C22H28N2O3/c1-23-15-13-21(14-16-23)27-22(25)24(19-6-4-3-5-7-19)17-12-18-8-10-20(26-2)11-9-18/h3-11,21H,12-17H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M1 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry method				Bioorg Med Chem Lett 29: 471-476 (2019) Article DOI: 10.1016/j.bmcl.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27SC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50518574 (CHEMBL4456775) Show SMILES COc1ccc(CCN(C(=O)OC2CCN(C)CC2)c2ccccc2)cc1 Show InChI InChI=1S/C22H28N2O3/c1-23-15-13-21(14-16-23)27-22(25)24(19-6-4-3-5-7-19)17-12-18-8-10-20(26-2)11-9-18/h3-11,21H,12-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry method				Bioorg Med Chem Lett 29: 471-476 (2019) Article DOI: 10.1016/j.bmcl.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27SC
					More data for this Ligand-Target Pair