BDBM50518662 CHEMBL4436938

SMILES: FC(F)(F)c1ccc(NS(=O)(=O)CSc2nnc(Br)n2Cc2ccc(Br)c3ccccc23)cn1

InChI Key: InChIKey=ZOCBZFYVBCXCPR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50518662 (CHEMBL4436938) Show SMILES FC(F)(F)c1ccc(NS(=O)(=O)CSc2nnc(Br)n2Cc2ccc(Br)c3ccccc23)cn1 Show InChI InChI=1S/C20H14Br2F3N5O2S2/c21-16-7-5-12(14-3-1-2-4-15(14)16)10-30-18(22)27-28-19(30)33-11-34(31,32)29-13-6-8-17(26-9-13)20(23,24)25/h1-9,29H,10-11H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake				Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036
					More data for this Ligand-Target Pair