BDBM50518675 CHEMBL4458898

SMILES: Brc1nnc(SCS(=O)(=O)Nc2cccnc2Br)n1Cc1ccc(Br)c2ccccc12

InChI Key: InChIKey=DFHINFXPYYBWIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50518675 (CHEMBL4458898) Show SMILES Brc1nnc(SCS(=O)(=O)Nc2cccnc2Br)n1Cc1ccc(Br)c2ccccc12 Show InChI InChI=1S/C19H14Br3N5O2S2/c20-15-8-7-12(13-4-1-2-5-14(13)15)10-27-18(22)24-25-19(27)30-11-31(28,29)26-16-6-3-9-23-17(16)21/h1-9,26H,10-11H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake				Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036
					More data for this Ligand-Target Pair