BDBM50518845 CHEMBL4473722

SMILES: Fc1c(Cl)cccc1C(=O)NNS(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=SQSCMNYNKQNGTI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT6A (Homo sapiens)	BDBM50518845 (CHEMBL4473722) Show SMILES Fc1c(Cl)cccc1C(=O)NNS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12ClFN2O3S/c18-15-7-3-6-14(16(15)19)17(22)20-21-25(23,24)13-9-8-11-4-1-2-5-12(11)10-13/h1-10,21H,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics CRC Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 62: 7146-7159 (2019) Article DOI: 10.1021/acs.jmedchem.9b00665
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A (Homo sapiens)	BDBM50518845 (CHEMBL4473722) Show SMILES Fc1c(Cl)cccc1C(=O)NNS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12ClFN2O3S/c18-15-7-3-6-14(16(15)19)17(22)20-21-25(23,24)13-9-8-11-4-1-2-5-12(11)10-13/h1-10,21H,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics CRC Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 15 uM acetyl c...				J Med Chem 62: 7146-7159 (2019) Article DOI: 10.1021/acs.jmedchem.9b00665
					More data for this Ligand-Target Pair