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SMILES: Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCc3ccccc3I)ccc12

InChI Key: InChIKey=HIXSBKGVUREKKC-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519192   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chloride anion exchanger


(Mus musculus)		BDBM50519192
PNG
(CHEMBL4466331)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCc3ccccc3I)ccc12
Show InChI InChI=1S/C20H17IO5/c1-11-14-7-8-17(25-10-13-5-3-4-6-16(13)21)12(2)19(14)26-20(24)15(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
More data for this
Ligand-Target Pair