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SMILES: Cc1c(OC2CCCC2)ccc2c(C)c(CC(O)=O)c(=O)oc12

InChI Key: InChIKey=SBZQXMHDTIKMQT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519201   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chloride anion exchanger


(Mus musculus)		BDBM50519201
PNG
(CHEMBL4591281)
Show SMILES Cc1c(OC2CCCC2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C18H20O5/c1-10-13-7-8-15(22-12-5-3-4-6-12)11(2)17(13)23-18(21)14(10)9-16(19)20/h7-8,12H,3-6,9H2,1-2H3,(H,19,20)
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
More data for this
Ligand-Target Pair