BDBM50519495 CHEMBL34023
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2[C@@H](O)CN=CNc12
InChI Key: InChIKey=YOOVTUPUBVHMPG-DANLAGSESA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine deaminase (Plasmodium falciparum) | BDBM50519495 (CHEMBL34023) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum ADA assessed as reduction in formation of ammonia using adenosine as substrate incubated for 15 mins by spectroph... | J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182 | |||||||||||
More data for this Ligand-Target Pair |