BDBM50519496 CHEMBL4439813

SMILES: OC[C@@H](Cn1cnc2c1[nH]c(=O)[nH]c2=O)n1cc(nn1)P(O)(O)=O

InChI Key: InChIKey=WCWKSYDPSRYDCU-RXMQYKEDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50519496 (CHEMBL4439813) Show SMILES OC[C@@H](Cn1cnc2c1[nH]c(=O)[nH]c2=O)n1cc(nn1)P(O)(O)=O |r| Show InChI InChI=1S/C10H12N7O6P/c18-3-5(17-2-6(14-15-17)24(21,22)23)1-16-4-11-7-8(16)12-10(20)13-9(7)19/h2,4-5,18H,1,3H2,(H2,21,22,23)(H2,12,13,19,20)/t5-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182
					More data for this Ligand-Target Pair