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SMILES: Nc1nc2n(C[C@H](CO)n3cc(nn3)P(O)(O)=O)cnc2c(=O)[nH]1

InChI Key: InChIKey=IGLCXHKMJKROMP-RXMQYKEDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519497   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50519497
PNG
(CHEMBL4546337)
Show SMILES Nc1nc2n(C[C@H](CO)n3cc(nn3)P(O)(O)=O)cnc2c(=O)[nH]1 |r|
Show InChI InChI=1S/C10H13N8O5P/c11-10-13-8-7(9(20)14-10)12-4-17(8)1-5(3-19)18-2-6(15-16-18)24(21,22)23/h2,4-5,19H,1,3H2,(H2,21,22,23)(H3,11,13,14,20)/t5-/m1/s1
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 100n/an/an/an/an/an/an/an/a



Universit£ Montpellier

Curated by ChEMBL


Assay Description
Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method

J Med Chem 62: 8365-8391 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00182
More data for this
Ligand-Target Pair