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SMILES: Nc1nc2n(C[C@@H](CO)OCCP(O)(O)=O)c(Br)nc2c(=O)[nH]1

InChI Key: InChIKey=SSHSIUPMQNBIBM-YFKPBYRVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519502   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50519502
PNG
(CHEMBL4452934)
Show SMILES Nc1nc2n(C[C@@H](CO)OCCP(O)(O)=O)c(Br)nc2c(=O)[nH]1 |r|
Show InChI InChI=1S/C10H15BrN5O6P/c11-9-13-6-7(14-10(12)15-8(6)18)16(9)3-5(4-17)22-1-2-23(19,20)21/h5,17H,1-4H2,(H2,19,20,21)(H3,12,14,15,18)/t5-/m0/s1
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 1.30E+4n/an/an/an/an/an/an/an/a



Universit£ Montpellier

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged HGPRT using Prib-PP as substrate by Hanes-plot based method

J Med Chem 62: 8365-8391 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00182
More data for this
Ligand-Target Pair