BDBM50519503 CHEMBL2420976
SMILES: Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1CCN(C1)C(=O)CP(O)(O)=O
InChI Key: InChIKey=DPSMTUGMQGDYNX-LURJTMIESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50519503 (CHEMBL2420976) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | 7.30E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier Curated by ChEMBL | Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method | J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182 | |||||||||||
More data for this Ligand-Target Pair |