BDBM50519743 CHEMBL4541016

SMILES: CCOC(=O)C1=C(C)NC(C)=C(C1c1ccc(OCCN2CCCCC2)c(Cl)c1)C(=O)OCC

InChI Key: InChIKey=DLRCMYPWZNEWKB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50519743 (CHEMBL4541016) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1ccc(OCCN2CCCCC2)c(Cl)c1)C(=O)OCC |c:5,10| Show InChI InChI=1S/C26H35ClN2O5/c1-5-32-25(30)22-17(3)28-18(4)23(26(31)33-6-2)24(22)19-10-11-21(20(27)16-19)34-15-14-29-12-8-7-9-13-29/h10-11,16,24,28H,5-9,12-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Bourgogne Franche-Comt£ Curated by ChEMBL					Assay Description Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...				J Med Chem 62: 11416-11422 (2019) Article DOI: 10.1021/acs.jmedchem.9b00937
					More data for this Ligand-Target Pair