BDBM50520272 CHEMBL4518152

SMILES: NC(=O)c1ccc(cc1OC1CCNCC1)-c1cccnc1

InChI Key: InChIKey=IZHBOEBZDIDTSZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50520272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520272 (CHEMBL4518152) Show SMILES NC(=O)c1ccc(cc1OC1CCNCC1)-c1cccnc1 Show InChI InChI=1S/C17H19N3O2/c18-17(21)15-4-3-12(13-2-1-7-20-11-13)10-16(15)22-14-5-8-19-9-6-14/h1-4,7,10-11,14,19H,5-6,8-9H2,(H2,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520272 (CHEMBL4518152) Show SMILES NC(=O)c1ccc(cc1OC1CCNCC1)-c1cccnc1 Show InChI InChI=1S/C17H19N3O2/c18-17(21)15-4-3-12(13-2-1-7-20-11-13)10-16(15)22-14-5-8-19-9-6-14/h1-4,7,10-11,14,19H,5-6,8-9H2,(H2,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582
					More data for this Ligand-Target Pair