BDBM50520563 CHEMBL4537710
SMILES: COc1cc(cc2CN([C@@H]3CCC(=O)NC3=O)C(=O)c12)N1CCN(CCCCCOc2ccc(cc2)[C@H]2[C@H](CCc3cc(O)ccc23)c2ccccc2)CC1
InChI Key: InChIKey=ZWKUCDGDWCSXJF-LOUBNBRRSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor (Homo sapiens (Human)) | BDBM50520563 (CHEMBL4537710) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of ERalpha in human T47D cells by ERE-driven luciferase reporter gene assay based target engagement assay | ACS Med Chem Lett 11: 407-408 (2020) Article DOI: 10.1021/acsmedchemlett.0c00071 | |||||||||||
More data for this Ligand-Target Pair |