BDBM50521019 CHEMBL4449816

SMILES: [H][C@@]1(CC[C@@]2([H])[C@H](CNc3ccc(O)cc3)CCC[C@]12C)[C@H](C)CCCC(C)(C)O

InChI Key: InChIKey=RKWXRWOSGFONGM-BWQUVUSJSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D receptor (Mus musculus)	BDBM50521019 (CHEMBL4449816) Show SMILES [H][C@@]1(CC[C@@]2([H])[C@H](CNc3ccc(O)cc3)CCC[C@]12C)[C@H](C)CCCC(C)(C)O |r| Show InChI InChI=1S/C25H41NO2/c1-18(7-5-15-24(2,3)28)22-13-14-23-19(8-6-16-25(22,23)4)17-26-20-9-11-21(27)12-10-20/h9-12,18-19,22-23,26-28H,5-8,13-17H2,1-4H3/t18-,19+,22-,23+,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Activation of VDR in mouse ASZ001 cells assessed as change in Cyp24A1 mRNA expression after 48 hrs by q-PCR analysis				Eur J Med Chem 162: 495-506 (2019) Article DOI: 10.1016/j.ejmech.2018.11.028
					More data for this Ligand-Target Pair