BDBM50521168 CHEMBL4445831

SMILES: Clc1ccc(CNCC2CCN(Cc3ccccc3Cl)CC2)cc1

InChI Key: InChIKey=WCVYQXYTLUYPOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50521168 (CHEMBL4445831) Show SMILES Clc1ccc(CNCC2CCN(Cc3ccccc3Cl)CC2)cc1 Show InChI InChI=1S/C20H24Cl2N2/c21-19-7-5-16(6-8-19)13-23-14-17-9-11-24(12-10-17)15-18-3-1-2-4-20(18)22/h1-8,17,23H,9-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [125I]-CXCL12 from human CXCR4 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysis				Eur J Med Chem 162: 631-649 (2019) Article DOI: 10.1016/j.ejmech.2018.10.060
					More data for this Ligand-Target Pair