BDBM50521296 CHEMBL4464435

SMILES: Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=IHEKUSLAEQDILG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50521296 (CHEMBL4464435) Show SMILES Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H17Cl2N3O2S/c1-13-8-17(29-12-21-26-19-4-2-3-5-20(19)30-21)6-7-18(13)27-22(28)25-16-10-14(23)9-15(24)11-16/h2-11H,12H2,1H3,(H2,25,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...				ACS Med Chem Lett 10: 62-66 (2019) Article DOI: 10.1021/acsmedchemlett.8b00415
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50521296 (CHEMBL4464435) Show SMILES Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H17Cl2N3O2S/c1-13-8-17(29-12-21-26-19-4-2-3-5-20(19)30-21)6-7-18(13)27-22(28)25-16-10-14(23)9-15(24)11-16/h2-11H,12H2,1H3,(H2,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...				ACS Med Chem Lett 10: 62-66 (2019) Article DOI: 10.1021/acsmedchemlett.8b00415
					More data for this Ligand-Target Pair