BDBM50521865 CHEMBL4445650

SMILES: OCc1ccc(cc1)C(=O)NCCC(=O)N[C@@H](Cc1cnnn1CCCCCCCCc1ccccc1)C(=O)NCc1cnnn1CCP(O)(O)=O

InChI Key: InChIKey=CXBGPTRHNUQBFI-YTTGMZPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50521865 (CHEMBL4445650) Show SMILES OCc1ccc(cc1)C(=O)NCCC(=O)N[C@@H](Cc1cnnn1CCCCCCCCc1ccccc1)C(=O)NCc1cnnn1CCP(O)(O)=O |r| Show InChI InChI=1S/C35H48N9O7P/c45-26-28-13-15-29(16-14-28)34(47)36-18-17-33(46)40-32(35(48)37-23-31-25-39-42-44(31)20-21-52(49,50)51)22-30-24-38-41-43(30)19-9-4-2-1-3-6-10-27-11-7-5-8-12-27/h5,7-8,11-16,24-25,32,45H,1-4,6,9-10,17-23,26H2,(H,36,47)(H,37,48)(H,40,46)(H2,49,50,51)/t32-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of PLK1 PBD (unknown origin) using GPMQSpTPLNG-OH as fluorescent probe incubated for 30 mins by fluorescence polarization assay				Bioorg Med Chem 27: 3511-3531 (2019) Article DOI: 10.1016/j.bmc.2019.07.005
					More data for this Ligand-Target Pair