BDBM50521955 CHEMBL4468865

SMILES: CC(C)c1nn(-c2ccc(F)cc2)c2nc(C)cc(C(O)=O)c12

InChI Key: InChIKey=NILAXMXJVAPBFA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50521955 (CHEMBL4468865) Show SMILES CC(C)c1nn(-c2ccc(F)cc2)c2nc(C)cc(C(O)=O)c12 Show InChI InChI=1S/C17H16FN3O2/c1-9(2)15-14-13(17(22)23)8-10(3)19-16(14)21(20-15)12-6-4-11(18)5-7-12/h4-9H,1-3H3,(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Transactivation of human GAL4-fused PPARalpha LBD expressed in human HepG2 cells after 24 hrs by renilla luciferase reporter gene assay				Bioorg Med Chem Lett 29: 2124-2128 (2019) Article DOI: 10.1016/j.bmcl.2019.06.062
					More data for this Ligand-Target Pair