BDBM50521967 CHEMBL4462038

SMILES: On1c(=O)[nH]c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2c1=O

InChI Key: InChIKey=QEOPPBYRXGTJPK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50521967 (CHEMBL4462038) Show SMILES On1c(=O)[nH]c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2c1=O Show InChI InChI=1S/C14H10FN3O5S/c15-8-1-4-10(5-2-8)24(22,23)17-9-3-6-12-11(7-9)13(19)18(21)14(20)16-12/h1-7,17,21H,(H,16,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNase H activity expressed in Escherichia coli using 32P-labeled template 31Trna RNA and DNA oligonucleotide...				Bioorg Med Chem 27: 3836-3845 (2019) Article DOI: 10.1016/j.bmc.2019.07.011
					More data for this Ligand-Target Pair