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SMILES: On1c(=O)[nH]c2cc(NS(=O)(=O)c3cccc(c3)C(F)(F)F)ccc2c1=O

InChI Key: InChIKey=SCZNWECTYWGASJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521981   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50521981
PNG
(CHEMBL4455408)
Show SMILES On1c(=O)[nH]c2cc(NS(=O)(=O)c3cccc(c3)C(F)(F)F)ccc2c1=O
Show InChI InChI=1S/C15H10F3N3O5S/c16-15(17,18)8-2-1-3-10(6-8)27(25,26)20-9-4-5-11-12(7-9)19-14(23)21(24)13(11)22/h1-7,20,24H,(H,19,23)
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.33E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase RNase H activity expressed in Escherichia coli using 32P-labeled template 31Trna RNA and DNA oligonucleotide...

Bioorg Med Chem 27: 3836-3845 (2019)


Article DOI: 10.1016/j.bmc.2019.07.011
More data for this
Ligand-Target Pair