BDBM50522699 CHEMBL3589107
SMILES: COc1cc2oc(cc(=O)c2c(O)c1-c1cc(ccc1O)-c1cc(=O)c2c(O)cc(O)cc2o1)-c1ccc(O)cc1
InChI Key: InChIKey=VFGDLHHMZWLHQG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50522699![]() (CHEMBL3589107) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Meiji Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assay | Bioorg Med Chem Lett 29: 1994-1997 (2019) Article DOI: 10.1016/j.bmcl.2019.05.020 | |||||||||||
More data for this Ligand-Target Pair |