null

SMILES: ONC(=O)CCc1csc(CCc2c[nH]c3ccccc23)n1

InChI Key: InChIKey=GKIICAXOUHWWTO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50522933 (CHEMBL4439017) Show SMILES ONC(=O)CCc1csc(CCc2c[nH]c3ccccc23)n1 Show InChI InChI=1S/C16H17N3O2S/c20-15(19-21)7-6-12-10-22-16(18-12)8-5-11-9-17-14-4-2-1-3-13(11)14/h1-4,9-10,17,21H,5-8H2,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate 3 pre-incubated for 30 mins followed by HDAC developer addition and measured a...				Bioorg Med Chem 27: 3408-3420 (2019) Article DOI: 10.1016/j.bmc.2019.06.036
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50522933 (CHEMBL4439017) Show SMILES ONC(=O)CCc1csc(CCc2c[nH]c3ccccc23)n1 Show InChI InChI=1S/C16H17N3O2S/c20-15(19-21)7-6-12-10-22-16(18-12)8-5-11-9-17-14-4-2-1-3-13(11)14/h1-4,9-10,17,21H,5-8H2,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate 3 pre-incubated for 30 mins followed by HDAC developer addition and measured a...				Bioorg Med Chem 27: 3408-3420 (2019) Article DOI: 10.1016/j.bmc.2019.06.036
					More data for this Ligand-Target Pair