BDBM50523805 CHEMBL4529655

SMILES: Cc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2ccc(Nc3ccco3)cc12

InChI Key: InChIKey=SUONQOFQAYZCSW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50523805 (CHEMBL4529655) Show SMILES Cc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2ccc(Nc3ccco3)cc12 Show InChI InChI=1S/C21H18N2O4/c1-13-4-6-14(7-5-13)18(24)12-21(26)16-11-15(22-19-3-2-10-27-19)8-9-17(16)23-20(21)25/h2-11,22,26H,12H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of recombinant human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured after 60 mins by ADP-Glo luminescence assay				Bioorg Med Chem 27: 1804-1817 (2019) Article DOI: 10.1016/j.bmc.2019.03.028
					More data for this Ligand-Target Pair