BDBM50523808 CHEMBL4474153

SMILES: COC(=O)Nc1ccc2NC(=O)\C(=C/c3ccc(O)cc3)c2c1

InChI Key: InChIKey=VCTGSTAOKPHFTO-ZSOIEALJSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50523808 (CHEMBL4474153) Show SMILES COC(=O)Nc1ccc2NC(=O)\C(=C/c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C17H14N2O4/c1-23-17(22)18-11-4-7-15-13(9-11)14(16(21)19-15)8-10-2-5-12(20)6-3-10/h2-9,20H,1H3,(H,18,22)(H,19,21)/b14-8-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of recombinant human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured after 60 mins by ADP-Glo luminescence assay				Bioorg Med Chem 27: 1804-1817 (2019) Article DOI: 10.1016/j.bmc.2019.03.028
					More data for this Ligand-Target Pair