BDBM50523809 CHEMBL4537467

SMILES: CC(=O)Nc1ccc2NC(=O)\C(=C/c3cccc(O)c3)c2c1

InChI Key: InChIKey=BVJZKQDBETZUEQ-NVNXTCNLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50523809 (CHEMBL4537467) Show SMILES CC(=O)Nc1ccc2NC(=O)\C(=C/c3cccc(O)c3)c2c1 Show InChI InChI=1S/C17H14N2O3/c1-10(20)18-12-5-6-16-14(9-12)15(17(22)19-16)8-11-3-2-4-13(21)7-11/h2-9,21H,1H3,(H,18,20)(H,19,22)/b15-8-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of recombinant human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured after 60 mins by ADP-Glo luminescence assay				Bioorg Med Chem 27: 1804-1817 (2019) Article DOI: 10.1016/j.bmc.2019.03.028
					More data for this Ligand-Target Pair