BDBM50523837 CHEMBL4454916

SMILES: Oc1ccc(\C=C2/C(=O)Nc3ccc(NC(=O)c4ccccc4)cc23)cc1

InChI Key: InChIKey=FGLCCFCTLCHUMF-UNOMPAQXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50523837 (CHEMBL4454916) Show SMILES Oc1ccc(\C=C2/C(=O)Nc3ccc(NC(=O)c4ccccc4)cc23)cc1 Show InChI InChI=1S/C22H16N2O3/c25-17-9-6-14(7-10-17)12-19-18-13-16(8-11-20(18)24-22(19)27)23-21(26)15-4-2-1-3-5-15/h1-13,25H,(H,23,26)(H,24,27)/b19-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of recombinant human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured after 60 mins by ADP-Glo luminescence assay				Bioorg Med Chem 27: 1804-1817 (2019) Article DOI: 10.1016/j.bmc.2019.03.028
					More data for this Ligand-Target Pair