null
SMILES: COc1cccc(NC2=Nc3ccc(Cl)cc3C(N2)(C#CC2CC2)C(F)(F)F)c1
InChI Key: InChIKey=POOBUACLMWERDQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50524502 (CHEMBL4561610) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as te... | Eur J Med Chem 176: 11-20 (2019) Article DOI: 10.1016/j.ejmech.2019.05.011 BindingDB Entry DOI: 10.7270/Q2F47SJC | |||||||||||
More data for this Ligand-Target Pair |