null

SMILES: CSc1nc(c([nH]1)-c1ccnc(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1)-c1ccc(F)cc1

InChI Key: InChIKey=ADYBWDFCCQVDNE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50524516 (CHEMBL4555766) Show SMILES CSc1nc(c([nH]1)-c1ccnc(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H18F4N4OS/c1-34-23-31-21(15-4-8-18(25)9-5-15)22(32-23)16-10-11-29-19(13-16)30-20(33)12-14-2-6-17(7-3-14)24(26,27)28/h2-11,13H,12H2,1H3,(H,31,32)(H,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant full length GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 min...				Eur J Med Chem 175: 309-329 (2019) Article DOI: 10.1016/j.ejmech.2019.04.035
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50524516 (CHEMBL4555766) Show SMILES CSc1nc(c([nH]1)-c1ccnc(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H18F4N4OS/c1-34-23-31-21(15-4-8-18(25)9-5-15)22(32-23)16-10-11-29-19(13-16)30-20(33)12-14-2-6-17(7-3-14)24(26,27)28/h2-11,13H,12H2,1H3,(H,31,32)(H,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISA				Eur J Med Chem 175: 309-329 (2019) Article DOI: 10.1016/j.ejmech.2019.04.035
					More data for this Ligand-Target Pair