null

SMILES: C[S+]([O-])c1nc(c([nH]1)-c1ccnc(NC(=O)C2CCC2)c1)-c1ccc(F)cc1

InChI Key: InChIKey=WLFQODQSEBJMDH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50524526 (CHEMBL4449570) Show SMILES C[S+]([O-])c1nc(c([nH]1)-c1ccnc(NC(=O)C2CCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O2S/c1-28(27)20-24-17(12-5-7-15(21)8-6-12)18(25-20)14-9-10-22-16(11-14)23-19(26)13-3-2-4-13/h5-11,13H,2-4H2,1H3,(H,24,25)(H,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	428	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant full length GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 min...				Eur J Med Chem 175: 309-329 (2019) Article DOI: 10.1016/j.ejmech.2019.04.035
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50524526 (CHEMBL4449570) Show SMILES C[S+]([O-])c1nc(c([nH]1)-c1ccnc(NC(=O)C2CCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O2S/c1-28(27)20-24-17(12-5-7-15(21)8-6-12)18(25-20)14-9-10-22-16(11-14)23-19(26)13-3-2-4-13/h5-11,13H,2-4H2,1H3,(H,24,25)(H,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISA				Eur J Med Chem 175: 309-329 (2019) Article DOI: 10.1016/j.ejmech.2019.04.035
					More data for this Ligand-Target Pair