BDBM50524864 CHEMBL4566670

SMILES: O[C@@]1(CCN(C1=O)c1ccccc1)C(=O)NCCc1cccs1

InChI Key: InChIKey=FZATYXICMFSLHR-KRWDZBQOSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50524864 (CHEMBL4566670) Show SMILES O[C@@]1(CCN(C1=O)c1ccccc1)C(=O)NCCc1cccs1 |r| Show InChI InChI=1S/C17H18N2O3S/c20-15(18-10-8-14-7-4-12-23-14)17(22)9-11-19(16(17)21)13-5-2-1-3-6-13/h1-7,12,22H,8-11H2,(H,18,20)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Healthcare Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...				J Med Chem 62: 5025-5039 (2019) Article DOI: 10.1021/acs.jmedchem.9b00041
					More data for this Ligand-Target Pair				3D Structure (crystal)