BDBM50524885 CHEMBL4445198

SMILES: FC(F)(F)c1cnc(NC(=O)CCCOc2ccccc2)o1

InChI Key: InChIKey=WDYCMBAHJGQKDX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 Tat protein (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524885 (CHEMBL4445198) Show SMILES FC(F)(F)c1cnc(NC(=O)CCCOc2ccccc2)o1 Show InChI InChI=1S/C14H13F3N2O3/c15-14(16,17)11-9-18-13(22-11)19-12(20)7-4-8-21-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462
					More data for this Ligand-Target Pair