BDBM50525061 CHEMBL4468620

SMILES: CCCOc1ccc(cc1-c1nc(CC)c(CC)c(=O)[nH]1)S(=O)(=O)N(CCO)CCN1CCOCC1

InChI Key: InChIKey=VPOFRWHZUWDYGG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50525061 (CHEMBL4468620) Show SMILES CCCOc1ccc(cc1-c1nc(CC)c(CC)c(=O)[nH]1)S(=O)(=O)N(CCO)CCN1CCOCC1 Show InChI InChI=1S/C25H38N4O6S/c1-4-15-35-23-8-7-19(18-21(23)24-26-22(6-3)20(5-2)25(31)27-24)36(32,33)29(11-14-30)10-9-28-12-16-34-17-13-28/h7-8,18,30H,4-6,9-17H2,1-3H3,(H,26,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human PDE5A1 expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate measured after 30 mins by sc...				J Med Chem 62: 4979-4990 (2019) Article DOI: 10.1021/acs.jmedchem.9b00123
					More data for this Ligand-Target Pair