BDBM50525355 CHEMBL4462235

SMILES: COc1ccc(CNc2nnc(N3CCCCC3)c3ccc(cc23)C(F)(F)F)cc1

InChI Key: InChIKey=QQIXLNQFLKSJTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525355 (CHEMBL4462235) Show SMILES COc1ccc(CNc2nnc(N3CCCCC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C22H23F3N4O/c1-30-17-8-5-15(6-9-17)14-26-20-19-13-16(22(23,24)25)7-10-18(19)21(28-27-20)29-11-3-2-4-12-29/h5-10,13H,2-4,11-12,14H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair