BDBM50525360 CHEMBL4565771

SMILES: COc1ccc(CNc2nnc(N3CCC(O)CC3)c3ccccc23)cc1

InChI Key: InChIKey=PFYGFJRIPJZNRF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525360 (CHEMBL4565771) Show SMILES COc1ccc(CNc2nnc(N3CCC(O)CC3)c3ccccc23)cc1 Show InChI InChI=1S/C21H24N4O2/c1-27-17-8-6-15(7-9-17)14-22-20-18-4-2-3-5-19(18)21(24-23-20)25-12-10-16(26)11-13-25/h2-9,16,26H,10-14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair