BDBM50525373 CHEMBL4473392

SMILES: C(Nc1nnc(-c2ccccc2)c2ccccc12)c1ccc2OCOc2c1

InChI Key: InChIKey=IBHJTJTWRDRRDX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525373 (CHEMBL4473392) Show SMILES C(Nc1nnc(-c2ccccc2)c2ccccc12)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H17N3O2/c1-2-6-16(7-3-1)21-17-8-4-5-9-18(17)22(25-24-21)23-13-15-10-11-19-20(12-15)27-14-26-19/h1-12H,13-14H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair