BDBM50525377 CHEMBL4555616

SMILES: Clc1cccc(Nc2nnc(N3CCCCC3)c3ccccc23)c1

InChI Key: InChIKey=NAOGWRITYAAJAG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525377 (CHEMBL4555616) Show SMILES Clc1cccc(Nc2nnc(N3CCCCC3)c3ccccc23)c1 Show InChI InChI=1S/C19H19ClN4/c20-14-7-6-8-15(13-14)21-18-16-9-2-3-10-17(16)19(23-22-18)24-11-4-1-5-12-24/h2-3,6-10,13H,1,4-5,11-12H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair