BDBM50525381 CHEMBL4534190

SMILES: FC(F)(F)c1cccc(c1)C(=O)NCc1ccc(cc1)N1CCCCC1

InChI Key: InChIKey=MZBUEJZQUQFXRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525381 (CHEMBL4534190) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C20H21F3N2O/c21-20(22,23)17-6-4-5-16(13-17)19(26)24-14-15-7-9-18(10-8-15)25-11-2-1-3-12-25/h4-10,13H,1-3,11-12,14H2,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair