BDBM50525388 CHEMBL4451127

SMILES: COc1ccc(CNc2nn(Cc3ccccc3)c3ccc(cc23)C(F)(F)F)cc1

InChI Key: InChIKey=QFENQPSNFZUYNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525388 (CHEMBL4451127) Show SMILES COc1ccc(CNc2nn(Cc3ccccc3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C23H20F3N3O/c1-30-19-10-7-16(8-11-19)14-27-22-20-13-18(23(24,25)26)9-12-21(20)29(28-22)15-17-5-3-2-4-6-17/h2-13H,14-15H2,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair