BindingDB logo
myBDB logout

BDBM50525392 CHEMBL4449807

SMILES: Clc1cccc(Nc2nncc3ccccc23)c1

InChI Key: InChIKey=FFFDPQUJMGZELA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525392   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 5A


(Bos taurus)
BDBM50525392
PNG
(CHEMBL4449807)
Show SMILES Clc1cccc(Nc2nncc3ccccc23)c1
Show InChI InChI=1S/C14H10ClN3/c15-11-5-3-6-12(8-11)17-14-13-7-2-1-4-10(13)9-16-18-14/h1-9H,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...


Eur J Med Chem 177: 269-290 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.026
More data for this
Ligand-Target Pair