BDBM50525393 CHEMBL4470619

SMILES: FC(F)(F)c1cccc(c1)C(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=VPZXJXSCXIOZAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50525393 (CHEMBL4470619) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClF3NO/c16-13-6-4-10(5-7-13)9-20-14(21)11-2-1-3-12(8-11)15(17,18)19/h1-8H,9H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of bovine aortic smooth muscle PDE5 using cGMP as substrate incubated for 30 mins in presence of EGTA and [3H]cGMP by liquid scintillation...				Eur J Med Chem 177: 269-290 (2019) Article DOI: 10.1016/j.ejmech.2019.05.026
					More data for this Ligand-Target Pair