BDBM50525405 CHEMBL4516678

SMILES: COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)Nc1ccccc1N

InChI Key: InChIKey=FYTIFTVQBOOGKZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50525405 (CHEMBL4516678) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)Nc1ccccc1N Show InChI InChI=1S/C26H30N2O4/c1-31-26(30)21-17-16-19-11-6-7-12-20(19)25(21)32-18-10-4-2-3-5-15-24(29)28-23-14-9-8-13-22(23)27/h6-9,11-14,16-17H,2-5,10,15,18,27H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.14E+3	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of HDAC in human MeT-5A cells assessed as increase in transfected YFP fused histone H3 acetylation treated at 8 hrs after YFP fused H3 tra...				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440
					More data for this Ligand-Target Pair