BDBM50525510 CHEMBL4574832

SMILES: OC(=O)c1ccc(Nc2ccnc(SCC(=O)c3ccc(Cl)cc3)n2)cc1

InChI Key: InChIKey=LFBGEWWFVHQYKC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50525510 (CHEMBL4574832) Show SMILES OC(=O)c1ccc(Nc2ccnc(SCC(=O)c3ccc(Cl)cc3)n2)cc1 Show InChI InChI=1S/C19H14ClN3O3S/c20-14-5-1-12(2-6-14)16(24)11-27-19-21-10-9-17(23-19)22-15-7-3-13(4-8-15)18(25)26/h1-10H,11H2,(H,25,26)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...				Eur J Med Chem 179: 707-722 (2019) Article DOI: 10.1016/j.ejmech.2019.06.063
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50525510 (CHEMBL4574832) Show SMILES OC(=O)c1ccc(Nc2ccnc(SCC(=O)c3ccc(Cl)cc3)n2)cc1 Show InChI InChI=1S/C19H14ClN3O3S/c20-14-5-1-12(2-6-14)16(24)11-27-19-21-10-9-17(23-19)22-15-7-3-13(4-8-15)18(25)26/h1-10H,11H2,(H,25,26)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of human wild type BRAF by Kinase-Glo luminescence assay				Eur J Med Chem 179: 707-722 (2019) Article DOI: 10.1016/j.ejmech.2019.06.063
					More data for this Ligand-Target Pair