BDBM50525516 CHEMBL4470636

SMILES: O=C(CSc1nccc(Nc2ccc(cc2)N2CCOCC2)n1)c1ccc(cc1)C#N

InChI Key: InChIKey=IZVOIBNYXWWLGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50525516 (CHEMBL4470636) Show SMILES O=C(CSc1nccc(Nc2ccc(cc2)N2CCOCC2)n1)c1ccc(cc1)C#N Show InChI InChI=1S/C23H21N5O2S/c24-15-17-1-3-18(4-2-17)21(29)16-31-23-25-10-9-22(27-23)26-19-5-7-20(8-6-19)28-11-13-30-14-12-28/h1-10H,11-14,16H2,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...				Eur J Med Chem 179: 707-722 (2019) Article DOI: 10.1016/j.ejmech.2019.06.063
					More data for this Ligand-Target Pair