BDBM50525594 CHEMBL4567363

SMILES: CCc1cc(cc(c1)C(C)(CC)CN)-c1ccnc2[nH]ncc12

InChI Key: InChIKey=MYWAEZQQJQKJIN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50525594 (CHEMBL4567363) Show SMILES CCc1cc(cc(c1)C(C)(CC)CN)-c1ccnc2[nH]ncc12 Show InChI InChI=1S/C19H24N4/c1-4-13-8-14(10-15(9-13)19(3,5-2)12-20)16-6-7-21-18-17(16)11-22-23-18/h6-11H,4-5,12,20H2,1-3H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6...				ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134
					More data for this Ligand-Target Pair