null

SMILES: ONC(=O)\C=C\c1ccc(CONC(=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=LXUGQSIPCDMDHL-FMIVXFBMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50525659 (CHEMBL4438702) Show SMILES ONC(=O)\C=C\c1ccc(CONC(=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C21H18N2O4/c24-20(22-26)12-9-15-5-7-16(8-6-15)14-27-23-21(25)19-11-10-17-3-1-2-4-18(17)13-19/h1-13,26H,14H2,(H,22,24)(H,23,25)/b12-9+	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.07.052
					More data for this Ligand-Target Pair
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50525659 (CHEMBL4438702) Show SMILES ONC(=O)\C=C\c1ccc(CONC(=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C21H18N2O4/c24-20(22-26)12-9-15-5-7-16(8-6-15)14-27-23-21(25)19-11-10-17-3-1-2-4-18(17)13-19/h1-13,26H,14H2,(H,22,24)(H,23,25)/b12-9+	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.07.052
					More data for this Ligand-Target Pair