null

SMILES: COc1cc(cc(OC)c1OC)C(=O)NOCc1ccc(\C=C\C(=O)NO)cc1

InChI Key: InChIKey=YZYKDCAQJIOPOU-CMDGGOBGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50525663 (CHEMBL4570738) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NOCc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C20H22N2O7/c1-26-16-10-15(11-17(27-2)19(16)28-3)20(24)22-29-12-14-6-4-13(5-7-14)8-9-18(23)21-25/h4-11,25H,12H2,1-3H3,(H,21,23)(H,22,24)/b9-8+	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.07.052
					More data for this Ligand-Target Pair
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50525663 (CHEMBL4570738) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NOCc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C20H22N2O7/c1-26-16-10-15(11-17(27-2)19(16)28-3)20(24)22-29-12-14-6-4-13(5-7-14)8-9-18(23)21-25/h4-11,25H,12H2,1-3H3,(H,21,23)(H,22,24)/b9-8+	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.07.052
					More data for this Ligand-Target Pair